Carcinoid tumours originate in the cells of the neuroendocrine system.  They have been classified according to their embryologic site of origin, such that foregut carcinoids start in the lungs, bronchi or stomach; midgut carcinoids start in the small intestine, appendix, or proximal large bowel; and hindgut carcinoid tumors start in the distal colon or rectum. The appendix presents the most frequent site of carcinoid tumours followed by the rectum, ileum, lungs, bronchi, and stomach. These neoplasms characteristically present in patients 50 to 60 years of age.

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